Description:
Glatiramer acetate is an immunomodulator drug currently used to treat multiple sclerosis. It is a random polymer of four amino acids found in myelin basic protein, namely L-glutamic acid, L-lysine, L-alanine, and L-tyrosine.
- Molecular Weight: 623.657
- Molecular Formula: C25H45N5O13
Canonical SMILES:
CC(C(=O)O)N.CC(=O)O.C1=CC(=CC=C1CC(C(=O)O)N)O.C(CCN)CC(C(=O)O)N.C(CC(=O)O)C(C(=O)O)N
InChI:
InChI=1S/C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2.C2H4O2/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;7-4-2-1-3-5(8)6(9)10;6-3(5(9)10)1-2-4(7)8;1-2(4)3(5)6;1-2(3)4/h1-4,8,11H,5,10H2,(H,12,13);5H,1-4,7-8H2,(H,9,10);3H,1-2,6H2,(H,7,8)(H,9,10);2H,4H2,1H3,(H,5,6);1H3,(H,3,4)/t8-;5-;3-;2-;/m0000./s1
InChIKey: FHEAIOHRHQGZPC-KIWGSFCNSA-N- Melting Point: >239°C
- Appearance: White to Off-white Soild
- Application: Multiple sclerosis (MS) is a chronic autoimmune illness that affects the central nervous system. Glatiramer acetate is one medicine used to treat MS. Glatiramer acetate is primarily used to treat multiple sclerosis (MS), but because of its immunomodulatory qualities and capacity to control inflammatory reactions, scientists have also looked at the possibility of using it in the drug discovery process for other illnesses.The mechanism of action of Glatiramer acetate is a crucial aspect of its application in the field of drug research. Glatiramer acetate is an immunomodulatory drug that has been shown to change the immune response from one that is pro-inflammatory to one that is anti-inflammatory. Treatment for a number of inflammatory and autoimmune illnesses may benefit from this immune system regulation. Scholars are investigating the potential of utilizing this method of action in the development of innovative treatments for ailments like lupus, rheumatoid arthritis, and inflammatory bowel illness.Furthermore, it has been demonstrated that Glatiramer acetate stimulates the development of regulatory T cells (Tregs), a subset of immune cells that support immunological tolerance and avert autoimmunity. This characteristic of Glatiramer acetate has generated attention in its possible use in the creation of treatments for illnesses like autoimmune disorders and allergies that are marked by dysregulated immune responses. Glatiramer acetate may provide a novel strategy for regulating immune responses and reestablishing immunological balance in these circumstances by encouraging the growth of Tregs.Furthermore, Glatiramer acetate possesses neuroprotective properties that have garnered attention in the field of neurodegenerative disease research. Studies have suggested that Glatiramer acetate may have the potential to protect nerve cells from damage and promote their survival in conditions such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). By exploring the neuroprotective effects of Glatiramer acetate, researchers aim to uncover new insights into the underlying mechanisms of neurodegeneration and develop treatments that target these pathways.Moreover, Glatiramer acetate has been investigated for its potential anti-cancer properties. Studies have shown that Glatiramer acetate can inhibit the growth and proliferation of certain cancer cell lines, suggesting a possible role in cancer therapy. Researchers are exploring the mechanisms by which Glatiramer acetate exerts its anti-cancer effects, with the goal of developing targeted therapies that leverage its anti-proliferative properties to treat various types of cancer.
Synonyms:
Copaxone; Copolymer 1; Copolymer-1
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