Germany
BuGuCh & Partners
Product Name: Shikimic acid
Synonyms:L-SHIKIMICACID;(3R,4S,5R)-3,4,5-TRIHYDROXY-1-CYCLOHEXENECARBOXYLIC ACID;(3R,4S,5R)-3,4,5-TRIHYDROXY-CYCLOHEX-1-ENECARBOXYLIC ACID;(3R,4S,5R)-3,4,5-TRIHYDROXYL-1-CYCLOHEXENE-1-CARBOXYLIC ACID;(3R,4S,5R)-TRIHYDROXY-1-CYCLOHEXENE-1-CARBOXYLIC ACID;(-)3ALPHA,4ALPHA,5BETA-TRIHYDROXY-1-CYCLOHEXENE-1-CARBOXYLIC ACID;
CAS: 138-59-0
MF:C7H10O5
MW:174.15
EINECS:205-334-2
Melting point:185-187 °C(lit.)
Refractive index:-180 ° (C=1, H2O)
density:0.96g/mL at 20 °C
storage temp. : -20°C Freezer
BRN ：4782717
Stability: Stable.
Package: 25kg/drum
Purity: 99%
Chemical properties:
White powder, soluble in water, the solubility in water 18g / 100ml, insoluble in chloroform, benzene and petroleum ether. 185 ° C to 191 ° C melting point, optical rotation -180 °, the smell of bitterness.
Pharmacological effects:
Shikimic acid by the impact of arachidonic acid metabolism, inhibition of platelet aggregation, inhibition of arterial and venous thrombosis and cerebral thrombosis, with anti-inflammatory, analgesic effect, but also as anti-virus and anti-cancer drug intermediates, but also with the prevention of avian influenza Drug 'Tamiflu', 'grams of influenza' role.
Usage:
Shikimic acid is a key precursor for the synthesis of many alkaloids, aryl amines, indole derivatives and chiral drugs. More recently, shikimic acid has been used as a starting material for oseltamivir (active ingredient in duffy), a neuraminidase inhibitor useful for the treatment and prevention of influenza A and influenza B.
Is an anti-tumor drug, but also the synthesis of anti-tumor drugs such as Diphenylmycin, glyoxalase inhibitors
