Molecular Weight: 329.43
Molecular Formula: C20H27NO3
Canonical SMILES: CC12CCC3C(C1CCC2O)CCC45C3(CC(=C(C4O5)O)C#N)C
InChI: InChI=1S/C20H27NO3/c1-18-7-6-14-12(13(18)3-4-15(18)22)5-8-20-17(24-20)16(23)11(10-21)9-19(14,20)2/h12-15,17,22-23H,3-9H2,1-2H3/t12-,13-,14-,15-,17+,18-,19+,20+/m0/s1
InChIKey: KVJXBPDAXMEYOA-CXANFOAXSA-N
Boiling Point: 516.5°C at 760 mmHg
Melting Point: 264°C
Purity: >98%
Solubility: Soluble in DMSO (17 mg/mL)
Storage: Store at -20°C
Synonyms: WIN24540; WIN-24540; WIN 24540; Trilostane; DB01108; D-01180; D 01180; Modrastane. Desopan; Modrenal
DescriptionTrilostane is an inhibitor of 3β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. It is used for the treatment of pituitary-dependent adrenocortical hormone hyperplasia in dogs and the treatment of adrenocortical hormone hyperplasia caused by adrenal cortex tumors in dogs.
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