Description:
Torin 2 is a potent and selective mTOR inhibitor with IC50 of 2.1 nM. It inhibits ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM, in PC3 cell lines respectively. It is potentially used as an antineoplastic agent.
- Molecular Weight: 432.406
- Molecular Formula: C24H15F3N4O
Purity: 98%
Canonical SMILES:
C1=CC(=CC(=C1)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C32)C5=CN=C(C=C5)N)C(F)(F)F
InChI:
InChI=1S/C24H15F3N4O/c25-24(26,27)17-2-1-3-18(11-17)31-22(32)9-6-16-13-29-20-7-4-14(10-19(20)23(16)31)15-5-8-21(28)30-12-15/h1-13H,(H2,28,30)
InChIKey: GUXXEUUYCAYESJ-UHFFFAOYSA-N
Synonyms:
Torin-2; Torin2; Torin 2; 9-(6-aminopyridin-3-yl)-1-[3-(trifluoromethyl)phenyl]benzo[h][1,6]naphthyridin-2-one
More details are to be found on supplier website
