Description:
Nelarabine acts by inhibiting DNA synthesis and inducing apoptosis in susceptible cells. Nelarabine demonstrated significant antineoplastic activity with acceptable toxicity.
- Molecular Weight: 297.27
- Molecular Formula: C11H15N5O5
Purity: ≥98% by HPLC
Canonical SMILES:
COC1=NC(=NC2=C1N=CN2C3C(C(C(O3)CO)O)O)N
InChI:
InChI=1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10-/m1/s1
InChIKey: IXOXBSCIXZEQEQ-UHTZMRCNSA-N
- Boiling Point: 721.0±70.0°C (Predicted)
- Melting Point: >206°C
- Solubility: Soluble in DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly, Sonicated)
- Appearance: White Solid
- Storage: Store at -20°C
Synonyms:
9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine; Arranon; MAY; Nelzarabine; 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine; NSC-686673; (2R,3S,4S,5R)-2-(2-Amino-6-methoxy-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
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