Description:
Silmitasertib is an orally bioavailable inhibitor of CK2 with potential antineoplastic activity. It inhibits proliferation in cancer cell lines overexpressing CK2. It suppresses survival and induces apoptosis of cancer stem cells including glioblastomas and acute myeloid leukemia cells.
- Molecular Weight: 349.774
- Molecular Formula: C19H12ClN3O2
Purity: >98%
Canonical SMILES:
C1=CC(=CC(=C1)Cl)NC2=C3C=CN=CC3=C4C=CC(=CC4=N2)C(=O)O
InChI:
InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)
InChIKey: MUOKSQABCJCOPU-UHFFFAOYSA-N
Synonyms:
CX-4945; CX 4945; 5-((3-Chlorophenyl)amino)benzo[c][2,6]naphthyridine-8-carboxylic acid
More details are to be found on supplier website