BGC > Buscar Producto > N-4-2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo-2,3-dpyrimidin-5-yl)ethylbenzoyll-glutamic acid | 165049-28-5

Molecular Formula: C24H29N5O6.C7H8O3S
Molecular Weight: 655.725

Description:
An impurity of Pemetrexed, which has been approved by FDA in 2004 for the treatment of malignant pleural mesothelioma (MPM) in combination with cisplatin, a platinum-containing chemotherapeutic drug.

• Molecular Weight:655.72
• Melting Point:> 192 °C (dec.)
• Purity:> 98%

Molecular Formula:
C31H37N5O9S
Canonical SMILES:
CCOC(=O)CCC(C(=O)OCC)NC(=O)C1=CC=C(C=C1)CCC2=CNC3=C2C(=O)NC(=N3)N.CC1=CC=C(C=C1)S(=O)(=O)O
InChI:
InChI=1S/C24H29N5O6.C7H8O3S/c1-3-34-18(30)12-11-17(23(33)35-4-2)27-21(31)15-8-5-14(6-9-15)7-10-16-13-26-20-19(16)22(32)29-24(25)28-20;1-6-2-4-7(5-3-6)11(8,9)10/h5-6,8-9,13,17H,3-4,7,10-12H2,1-2H3,(H,27,31)(H4,25,26,28,29,32);2-5H,1H3,(H,8,9,10)/t17-;/m0./s1
InChIKey:
UANBXQTVHOIGGQ-LMOVPXPDSA-N
Solubility:
Very slightly soluble in Dichloromethane; Slightly soluble in DMF (Sonicated), DMSO
Appearance:
Off-white to Pale Brown Solid
Storage: 2-8 °C
Synonyms:
(S)-Diethyl 2-(4-(2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioate 4-methylbenzenesulfonate; N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]L-glutamic acid; 4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl-L-glutamic acid diethyl ester p-toluenesulfonate salt