BGC > Product Search > 9H-Purine-9-acetamide,N-ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-N-(phenylmethyl)- | 226954-04-7

Molecular Formula: C23H23N5O2
Molecular Weight: 401.468

Description:
Exhibits high affinity for TSPO in rat whole brain (Ki = 0.297 nM), and high potency against human and rat glial TSPO (IC50 values are 2.73 and 3.04 nM respectively). Displays no noticeable binding to a number of other receptors, transporters or ion channels. Also displays anxiolytic and antidepressant effects in rodent models, without inducing benzodiazepine-like adverse effects.

• Molecular Weight:401.46
• Purity:>98%

Molecular Formula:
C23H23N5O2
Canonical SMILES:
CCN(CC1=CC=CC=C1)C(=O)CN2C3=NC(=NC=C3N(C2=O)C)C4=CC=CC=C4
InChI:
InChI=1S/C23H23N5O2/c1-3-27(15-17-10-6-4-7-11-17)20(29)16-28-22-19(26(2)23(28)30)14-24-21(25-22)18-12-8-5-9-13-18/h4-14H,3,15-16H2,1-2H3
InChIKey:
NBMBIEOUVBHEBM-UHFFFAOYSA-N
Synonyms:
AC-5216; AC 5216; AC5216; XBD-173; XBD 173; XBD173; Emapunil.