BGC > Product Search > Seneciphyllin | 480-81-9

Molecular Formula: C18H23NO5
Molecular Weight: 333.38
Hazard Symbols: T
UN Number: 1544
WGKGermany: 3
PackingGroup: III

Description:
Seneciphylline, a natural pyrrolizidine alkaloid isolated from the herbs of Senecio scandens, may cause reduction of cytochrome P-450 and related monooxygenase activities. Seneciphylline is a pyrrolizidine alkaloid with the potential to affect hepatic drug metabolizing enzymes in rat cells. In vitro, seneciphylline has no effection on hepatic drug metabolizing enzymes, but has seneciphyllineslight activity of reducing aminopyrine demethylase.

• Molecular Weight:333.4
• Boiling Point:470.34°C (rough estimate)
• Melting Point:217°C
• Purity:>98%

Molecular Formula:
C18H23NO5
Canonical SMILES:
CC=C1CC(=C)C(C(=O)OCC2=CCN3C2C(CC3)OC1=O)(C)O
InChI:
InChI=1S/C18H23NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,14-15,22H,2,6-10H2,1,3H3/b12-4-/t14-,15-,18-/m1/s1
InChIKey:
FCEVNJIUIMLVML-QPSVUOIXSA-N
Solubility:
less than 0.1 mg/mL at 64 °F
Appearance:
Powder
Storage: -20°C
Synonyms:
Jacodine; (15cis)-12-Hydroxy-13,19-didehydrosenecionan-11,16-dione; 13,19-didehydro-12-hydroxysenecionan-11,16-dione