BGC > Product Search > L-Glutathione (oxidized form) | 27025-41-8

Assay	98.0% --101.0%
Appearance	White or almost white, crystalline powder or colorless crystals.
Odor & Taste	Characteristic
Mesh Size	100 mesh 100
Solubility	Freely soluble in water, very slightly soluble in ethanol and in methylene chloride.
Loss on Drying	Maximum0.5%
Total Ash	Maximum0.3%
Specific optical rotation	- 15.5 --- - 17.5
Related substances	Complies with standard of EP 2007.
Chlorides	Maximum 200 ppm
Sulphates	Maximum 300 ppm
Ammonium	Maximum 200 ppm
Iron	Maximum 10 ppm.
Residue on Ignition	Maximum0.1%
Sulphated ash	Maximum 0.1%
Heavy Metals	Maximum10 PPM
As	Maximum2 PPM
Cd	Maximum1 PPM
Pb	Maximum1 PPM
Hg	Maximum0.5 PPM
Mierobiology
Total Plate Count	≤ 1000cfu/g
Total Yeast & Mold	≤ 100cfu/g
E. Coli	Negative
Salmonella	Negative
Staphylococcus	Negative

Molecular Formula: C20H32N6O12S2
Molecular Weight: 612.63
Hazard Symbols: Xi
WGKGermany: 2
HS Code: 29309090

Package: 1kg per bag and 25kg per drum
Price: usd1200.0/kg (Dec. 2022)

Description:
Oxiglutatione is a stabilized formulation of disodium glutathione disulfide (GSSG; oxidized glutathione) and cisplatin (1000:1) with potential chemoprotective and immunomodulating activities. Mimicking endogenous GSSG, Oxiglutatione acts as a competitive substrate for gamma-glutamyl-transpeptidase (GGT), which may result in the S-glutathionylation of proteins, predominantly actin, a redox stress on endoplasmic reticulum (ER), and ER stress-induced apoptosis. S-glutathionylation may be stimulated by reactive oxygen species (ROS) liberated by an oxiglutatione-induced increase in GGT activity. Oxiglutatione may also induce phosphorylation of proteins such as ERK and p38, two kinases that play critical regulatory roles in cell proliferation and apoptosis. The cisplatin component of this agent does not provide an effective therapeutic concentration of cisplatin in vivo.

• Molecular Weight:612.63
• Melting Point:>168°C
• Purity:>98%

Molecular Formula:
C20H32N6O12S2
Canonical SMILES:
C(CC(=O)NC(CSSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N)C(=O)NCC(=O)O)C(C(=O)O)N
InChI:
InChI=1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1
InChIKey:
YPZRWBKMTBYPTK-BJDJZHNGSA-N
Appearance:
white solid powder
Synonyms:
L-Glutathione Oxidised; Oxiglutatione; glutathione disulfide; GSSG; NOV-002; NOV 002; NOV002

Purity: 95%
Smile code: OC([C@H](CCC(N[C@@H](CSSC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)C(NCC(O)=O)=O)=O)N)=O
MDL Number: MFCD00063106
MolFormula: C20H32N6O12S2
MolWeight: 612.6311
Available in stock: 2010.982

Smile code:
OC([C@H](CCC(N[C@@H](CSSC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)C(NCC(O)=O)=O)=O)N)=O
MDL Number:
MFCD00063106
Purity :
95%
Available in stock:
1516.205 g