Description:
Salcaprozate sodium (SNAC) is used as an excipient in drug formulation as a chemical permeation enhancer (PE) to aid the oral absorption of macromolecules, peptides and proteins such as insulin (diabetes), heparin (heart attacks and angina) and cyanocobalamin (vitamin B12 deficiency and anaemia) which would otherwise have poor bioavailability. SNAC is considered to be safe for human consumption (GRAS) by the FDA.
- Molecular Weight:301.31
- Boiling Point:521.7 °C at 760 mmHg
- Purity:98%
Molecular Formula:
C15H20NNaO4
Canonical SMILES:
C1=CC=C(C(=C1)C(=O)NCCCCCCCC(=O)[O-])O.[Na+]
InChI:
InChI=1S/C15H21NO4.Na/c17-13-9-6-5-8-12(13)15(20)16-11-7-3-1-2-4-10-14(18)19; /h5-6,8-9,17H,1-4,7,10-11H2,(H,16,20)(H,18,19); /q; +1/p-1
InChIKey:
UOENJXXSKABLJL-UHFFFAOYSA-M
Appearance:
White to pale yellow powder
Storage: 2 - 8 °C. Store in a tightly closed container.
Synonyms:
sodium 8-(2-hydroxybenzamido)octanoate; SNAC More details are to be found
here