Description:
E6446 is a novel synthetic antagonist for nucleic acid-sensing TLRs.
Molecular Formula:
C27H37Cl2N3O3
Canonical SMILES:
C1CCN(C1)CCCOC2=CC=C(C=C2)C3=NC4=C(O3)C=C(C=C4)OCCCN5CCCC5.Cl.Cl
InChI:
InChI=1S/C27H35N3O3.2ClH/c1-2-14-29(13-1)17-5-19-31-23-9-7-22(8-10-23)27-28-25-12-11-24(21-26(25)33-27)32-20-6-18-30-15-3-4-16-30;;/h7-12,21H,1-6,13-20H2;2*1H
InChIKey:
DQOUZINBHKWGGM-UHFFFAOYSA-N
Solubility:
DMSO: > 7.6 mg/mL
Appearance:
White to Off-White Solid
Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Synonyms:
E-6446 dihydrochloride; E 6446 dihydrochloride; E6446 dihydrochloride; 6-(3-(pyrrolidin-1-yl)propoxy)-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)benzo[d]oxazole dihydrochloride More details are to be found
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