BGC > Product Search > Rifamycin O | 14487-05-9

Molecular Formula: C39H47NO14
Molecular Weight: 753.79

Description:
Rifaximin EP Impurity F is an intermediate of Rifaximin. Rifaximin is a semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. It also acts as a pregnane X receptor (PXR) agonist. It is approved for the treatment of traveler's diarrhea, irritable bowel syndrome, and hepatic encephalopathy.

• Molecular Weight:753.79
• Boiling Point:972.8°C at 760 mmHg
• Melting Point:>171°C (dec.)
• Purity:99%

Molecular Formula:
C39H47NO14
Canonical SMILES:
CC1C=CC=C(C(=O)NC2=CC3(C4=C(C2=O)C(=C(C5=C4C(=O)C(O5)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)OCC(=O)O3)C
InChI:
InChI=1S/C39H47NO14/c1-17-11-10-12-18(2)37(48)40-24-15-39(51-16-26(42)53-39)29-27(33(24)46)32(45)22(6)35-28(29)36(47)38(8,54-35)50-14-13-25(49-9)19(3)34(52-23(7)41)21(5)31(44)20(4)30(17)43/h10-15,17,19-21,25,30-31,34,43-45H,16H2,1-9H3,(H,40,48)/b11-10+,14-13+,18-12-/t17-,19+,20+,21+,25-,30-,31+,34+,38-,39?/m0/s1
InChIKey:
RAFHKEAPVIWLJC-KQOHHTLASA-N
Solubility:
Soluble in Chloroform (Slightly), Methanol (Slightly, Heated)
Appearance:
Yellow to Dark Yellow Solid
Application:
Rifaximin intermediate.
Storage: Store at -20°C
Synonyms:
Rifamycin O; 4-O-(Carboxymethyl)-1-deoxy-1,4-dihydro-4-hydroxy-1-oxo-rifamycin γ-Lactone