Suppliers for CAS
481-74-3
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Properties | CAS |
481-74-3 | Formula |
C15H10O4 | EINECS |
207-572-2 |
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19 Registered suppliers
Simagchem Corporation
P.R.China
Xiamen Hisunny Chemical Co., Ltd.
P.R.China
Molecular Formula: C15H10O4
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
H&Z Industry Co.,Ltd
P.R.China
Xingrui Industry Co., Limited
P.R.China
Hangzhou Meite Industry Co., Ltd (Hangzhou Meite Chemical Co., Ltd)
P.R.China
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C15H10O4 Molecular Weight: 254.24 Hazard Symbols: Xi WGKGermany: 3 HS Code: 29146990
Sigma-Aldrich International GmbH
Switzerland
Tianjin YR Chemspec Technology Co.,Ltd.
P.R.China
Appearance | Orange Powder
| Odor &Taste | Characteristic
| Specification | 98%
| Active Ingredient | Chrysophanol / Chrysophanic Acid
| Sieve Analysis | NLT 100% pass 80 mesh
| Loss on Drying | ≤ 4.0%
| Ash content | ≤ 2.0%
| Ethanol | <=5000ppm
| Total Heavy Metals | ≤ 20ppm
| Total Plate Count | ≤ 1000cfu/g
| Total Yeast & Mold | ≤ 100cfu/g |
Shandong Ench Chemical Co.,Ltd
P.R.China
Skyrun Industrial Co., Ltd.
P.R.China
BOC Sciences
USA
Description: Chrysophanic acid (Chrysophanol) is a natural anthraquinone with anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. Chrysophanic acid preferentially blocked proliferation in SNU-C5 cells but not in other cell lines (HT7, HT29, KM12C, SW480, HCT116 and SNU-C4) with low levels of EGFR expression. Chrysophanic acid treatment in SNU-C5 cells inhibited EGF-induced phosphorylation of EGFR and suppressed activation of downstream signaling molecules, such as AKT, extracellular signal-regulated kinase (ERK) and the mammalian target of rapamycin (mTOR)/ribosomal protein S6 kinase (p70S6K). Chrysophanic acid (80 and 120 µm) significantly blocked cell proliferation when combined with the mTOR inhibitor, rapamycin. These findings offer the first evidence of anticancer activity for chrysophanic acid via EGFR/mTOR mediated signaling transduction pathway. Chrysophanol is a natural compound found in the roots and rhizomes of Rheum palmatum L. It can be used in cosmetics material. - Molecular Weight:254.24
- Boiling Point:Sublimes
- Melting Point:194-197 ℃
- Purity:≥ 98 %
Molecular Formula: C15H10O4 Canonical SMILES: CC1=CC(=C2C(=C1)C(=O)C3=C(C2=O)C(=CC=C3)O)O InChI: InChI=1S/C15H10O4/c1-7-5-9-13(11(17)6-7)15(19)12-8(14(9)18)3-2-4-10(12)16/h2-6,16-17H,1H3 InChIKey: LQGUBLBATBMXHT-UHFFFAOYSA-N Solubility: less than 1 mg/mL at 64 °F Appearance: Orange solid Application: anti-inflammatory Synonyms: 1,8-dihydroxy-3-methylanthracene-9,10-dione More details are to be found here
Ambeed, Inc.
USA
Purity: 98% Smile code: O=C1C2=C(C=CC=C2O)C(C3=CC(C)=CC(O)=C13)=O MDL Number: MFCD00001208 MolFormula: C15H10O4 MolWeight: 254.2375 Available in stock: 13.097 More details are to be found here
BLD Pharmatech Ltd
P.R.China
Smile code:O=C1C2=C(C=CC=C2O)C(C3=CC(C)=CC(O)=C13)=O MDL Number:MFCD00001208 Purity :98% Available in stock: 17.905 g More details are to be found here
Xiamen Equation Chemical Co.,Ltd
P.R.China
Chemos GmbH & Co. KG
Germany
BuGuCh & Partners
Germany
CM Fine Chemicals
Switzerland
Santa Cruz Biotechnology, Inc.
USA
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