BGC > Product Search > INCB018424 | 941678-49-5

Molecular Formula: C17H18N6
Molecular Weight: 306.371
HS Code: 29335990

Description:
Ruxolitinib is a potent and selective JAK1/2 inhibitor with IC50 values of 3.3 nM and 2.8 nM respectively in cell-free assays, and has > 130-fold selectivity for JAK1/2 versus JAK3.

• Molecular Weight:306.37
• Melting Point:84-89°C
• Purity:>98%

Molecular Formula:
C17H18N6
Canonical SMILES:
C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
InChI:
InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1
InChIKey:
HFNKQEVNSGCOJV-OAHLLOKOSA-N
Solubility:
Soluble in aqueous buffers across a pH of 1-8
Appearance:
White to Off-white Solid
Synonyms:
(R)-Ruxolitinib; INCB018424; R-INCB018424; (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile

Purity: 98%
Smile code: N#CC[C@]([H])(C1CCCC1)N2C=C(C=N2)C3=C4C=CN=C4NC=N3
MDL Number: MFCD12031592
MolFormula: C17H18N6
MolWeight: 306.3650
Available in stock: 22.711

Smile code:
N#CC[C@]([H])(C1CCCC1)N2C=C(C=N2)C3=C4C=CN=C4NC=N3
MDL Number:
MFCD12031592
Purity :
98%
Available in stock:
32.237 g