BGC > CAS Search > 920509-32-6

Molecular formula :C17H12Cl2N6O4

EINECS :
Molecular formula :C17H12Cl2N6O4

Description :
MGL-3196 is a first-in-class, orally available, once-daily and liver-directed thyroid hormone receptor (THR) beta-selective agonist. Studies suggest that MGL-3196 has an attractive, differentiated profile as a potential treatment for non-alcoholic steatohepatitis (NASH) and dyslipidemias.

• Molecular Weight :435.211

Molecular Formula :
C17H12Cl2N6O4
Canonical SMILES :
CC(C)C1=CC(=NNC1=O)OC2=C(C=C(C=C2Cl)N3C(=O)NC(=O)C(=N3)C#N)Cl
InChI :
InChI=1S/C17H12Cl2N6O4/c1-7(2)9-5-13(22-23-15(9)26)29-14-10(18)3-8(4-11(14)19)25-17(28)21-16(27)12(6-20)24-25/h3-5,7H,1-2H3,(H,23,26)(H,21,27,28)
InChIKey :
FDBYIYFVSAHJLY-UHFFFAOYSA-N
Application :
potential treatment for non-alcoholic steatohepatitis (NASH) and dyslipidemias
Synonyms :
CHEMBL3261331; UNII-RE0V0T1ES0; MGL-3196; MGL 3196; MGL3196; VIA 3196; VIA3196; VIA-3196; Resmetirom.RE0V0T1ES0; 2-[3,5-dichloro-4-[(6-oxo-5-propan-2-yl-1H-pyridazin-3-yl)oxy]phenyl]-3,5-dioxo-1,2,4-triazine-6-carbonitrile

More details are to be found here

Smile code:
N#CC1=NN(C2=CC(Cl)=C(OC(C=C3C(C)C)=NNC3=O)C(Cl)=C2)C(NC1=O)=O
MDL Number:
MFCD26142653
Purity :
99%
Available in stock:
32.594 g