BGC > CAS Search > 78110-38-0

Appearance	White, odorless crystalline powder
Identification	The retention times of the major peaks in the chromatogram of the assay preparation correspond to those of the Standard preparation obtained in the assay
Color of Solution	Not more than yellow or
greenish- yellow Reference Solution II
Clarity of solution	Not more than Turbidity Standard I
PH	4.5~7.5
RelatedImpurities
Single impurities	Not more than1.0%
Total impurities	Not more than3.0%
Water Content	Not more than 2.0%
Residue of ignition	Not more than 0.1%
Heavy Metals	Not more than 30ppm
Bacterial Endotoxins	Not more than 0.17EU/mg (Aztreonam)
Sterility Test	Sterile (without germs in 14 days)
Particulate matter	≥ 10µm, no more than 2500/g ≥ 25µm, no more than 250/g
Assay	Contain C13H17N5O8S2 90.0% ~105.0%(Calculated on anhydrous substance without L-Arginine )
L-Arginine content	42%~45%

Molecular Formula: C13H17N5O8S2
Molecular Weight: 435,43

Description:
Aztreonam inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking. It has a very high affinity for penicillin-binding protein-3 and mild affinity for penicillin-binding protein-1a. Aztreonam binds the penicillin-binding proteins of Gram-positive and anaerobic bacteria very poorly and is largely ineffective against them.

• Molecular Weight:435.43
• Melting Point:>184°C (dec.)
• Purity:>98%

Molecular Formula:
C13H17N5O8S2
Canonical SMILES:
CC1C(C(=O)N1S(=O)(=O)O)NC(=O)C(=NOC(C)(C)C(=O)O)C2=CSC(=N2)N
InChI:
InChI=1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1
InChIKey:
WZPBZJONDBGPKJ-VEHQQRBSSA-N
Solubility:
Soluble in DMSO (Slightly), Water (Slightly, Heated, Sonicated)
Appearance:
White Solid
Storage: Store at -20°C
Synonyms:
Propanoic acid, 2-[[(Z)-[1-(2-amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methyl-; Az threonam; Az-threonam; Azactam; Azthreonam; Urobactam; 2-[[(Z)-[1-(2-Amino-4-thiazolyl)-2-[[(2S,3S)-2-methyl-4-oxo-1-sulfo-3-azetidinyl]amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid; Propanoic acid, 2-[[[1-(2-amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methyl-, [2S-[2α,3β(Z)]]-; Antibiotic Squibb 26,776; Azonam; Aztreon; Nebactam; Primbactam; SQ 26776; Squibb 26776