BGC > CAS Search > 1094-61-7

Appearance: White Crystal Powder | Taste: Characteristic | Odor: Characteristic | Assay: 98.5% ~ 101.5% | Particle Size: NLT 100% Through 80 mesh | Loss on Drying:<2.0%

Package: 100g 1kg.
Delivery time:within2days after get payment.

Molecular Formula: C11H15N2O8P
Molecular Weight: 334.22
WGKGermany: 3

Food additives

Spec.: FOOD
Content: 99%
e.evalue: 100%

Appearance	White to yellowish powder
NMN Purity by HPLC	98%min
Water content(KF)	≤ 5%
Residual solvent	EtOH ≤ 2.0%
Sodium content	≤ 1.0%
Pb	≤ 0.5ppm
Hg	≤ 0.5ppm
Cd	≤ 0.5ppm
Total microbial count	≤ 750cfu/g
E.coli	≤ 3MPN/g

Assay(HPLC)	99% min.
Water	1% max.
PH	2-5
Heavy metal	1ppm max.
Total microbial count	100CFU/g max.
Appearance	White powder

Assay(HPLC): 99% min. | Water: 1% max. | PH: 2-5 | Heavy metal: 1ppm max. | Total microbial count: 100CFU/g max. | Appearance: White powder

Assay(HPLC)	99% min.
Water	1% max.
PH	2-5
Heavy metal	1ppm max.
Total microbial count	100CFU/g max.
Appearance	White powder

beta-Nicotinamide mononucleotide
A product of the eNAMPT reaction and a NAD+ intermediate
Assay: 99%

Category: Coenzyme/ Nucleoside

Description:
β-Nicotinamide mononucleotide, a major product of extracellular NAMPT reaction, could ameliorate glucose intolerance and also increase hepatic insulin sensitivity and sorts of gene expression involved in inflammatory response, oxidative stress and so on. Nutritional supplement in health care products.

• Molecular Weight:334.22
• Purity:≥95%

Molecular Formula:
C11H15N2O8P
Canonical SMILES:
O[C@H]1[C@@H](O)[C@H]([N+]2=CC(C(N)=O)=CC=C2)O[C@@H]1COP(O)([O-])=O
InChI:
1S/C11H15N2O8P/c12-10(16)6-2-1-3-13(4-6)11-9(15)8(14)7(21-11)5-20-22(17,18)19/h1-4,7-9,11,14-15H,5H2,(H3-,12,16,17,18,19)/t7-,8-,9-,11-/m1/s1
InChIKey:
DAYLJWODMCOQEW-TURQNECASA-N
Solubility:
H2O: ≥ 35 mg/mL
Appearance:
White to Off-White Powder
Application:
Ingredient of health care products.
Storage: -20ºC Freeze
Synonyms:
Nicotinamide Mononucleotide; NMN; β-NMN; β-Nicotinamide mononucleotide; BETA-NMN;BETA-NICOTINAMIDE MONONUCLEOTIDE;BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE;NMN;NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5'-PHOSPHATE;NICOTINAMIDE RIBOTIDE;NICOTINAMIDE MONONUCLEOTIDE;3-(aminocarbonyl)-1-(5-O-phosphonato-beta-D-ribofuranosyl)pyrid

Purity: 97%
Smile code: O=P(OC[C@H]1O[C@@H]([N+]2=CC=CC(C(N)=O)=C2)[C@H](O)[C@@H]1O)([O-])O
MDL Number: MFCD00038748
MolFormula: C11H15N2O8P
MolWeight: 334.2192
Available in stock: 582.3

Smile code:
O=P(OC[C@H]1O[C@@H]([N+]2=CC=CC(C(N)=O)=C2)[C@H](O)[C@@H]1O)([O-])O
MDL Number:
MFCD00038748
Purity :
97%
Available in stock:
416 g

NMN (Nicotinamide mononucleotide): The full name is \"β-nicotinamide mononucleotide\"

Because nicotinamide belongs to vitamin B3, NMN belongs to the category of vitamin B derivatives. It is widely involved in a number of biochemical reactions in the human body and is closely related to immunity and metabolism.

Supplementation of NMN increases the NAD+ content in the body, thereby delaying, improving, and preventing various phenotypes related to aging, or age-induced metabolic disorders, senile diseases, and so on.

NMN can also adjust the biological clock law, delay aging, generate energy required for life activities, strengthen immunity, repair the nervous system, prevent three highs and diabetes, prevent cardiovascular and cerebrovascular diseases, and repair genes It can repair kidney damage, speed up metabolism, help restore menopause, protect eyesight and hearing, have a weight loss effect, can treat hair loss, improve hair quality, improve female fertility, help whitening, moisturizing, and compact Facial muscles, improve triangular eyes caused by falling eyelids.

Reduced Nicotinamide Mononucleotide (NMNH) Potently Enhances NAD and Suppresses Glycolysis, the TCA Cycle, and Cell Growth

Abstract
Decreased cellular NAD levels are causally linked to aging and aging-associated diseases. NAD precursors in oxidized form such as nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR) have gained much attention and been well studied for their ability to restore NAD levels in model organisms. Less is known about whether NAD precursors in reduced form can also efficiently increase the tissue and cellular NAD levels and have different effects on cellular processes than NMN or NR. In the present study, we developed a chemical method to produce dihydronicotinamide mononucleotide (NMNH), which is the reduced form of NMN. We demonstrated that NMNH was a better NAD enhancer than NMN both in vitro and in vivo, mediated by nicotinamide mononucleotide adenylyltransferase (NMNAT). Additionally, NMNH increased the reduced NAD (NADH) levels in cells and in mouse livers. Metabolomic analysis revealed that NMNH inhibited glycolysis and the TCA cycle. In vitro experiments demonstrated that NMNH induced cell cycle arrest and suppressed cell growth. Nevertheless, NMNH treatment did not cause an observable difference in mouse weight. Taken together, our work demonstrates that NMNH is a potent NAD enhancer and suppresses glycolysis, the TCA cycle, and cell growth.

This component belongs to the family of Enzyme