BGC > Product Search > 6,7-Diphenyl-2-sulfanylidene-1H-pteridin-4-one | 14892-97-8

Molecular Formula: C18H12N4OS
Molecular Weight: 332.39

Description:
SCR7 pyrazine is a DNA Ligase IV inhibitor. SCR7 pyrazine has been shown to potentiate CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold, and inhibits nonhomologous end-joining (NHEJ).

• Molecular Weight:332.38
• Melting Point:206-208°C
• Purity:≥98% by HPLC

Molecular Formula:
C18H12N4OS
Canonical SMILES:
C1=CC=C(C=C1)C2=NC3=C(NC(=S)NC3=O)N=C2C4=CC=CC=C4
InChI:
InChI=1S/C18H12N4OS/c23-17-15-16(21-18(24)22-17)20-14(12-9-5-2-6-10-12)13(19-15)11-7-3-1-4-8-11/h1-10H,(H2,20,21,22,23,24)
InChIKey:
GSRTWXVBHGOUBU-UHFFFAOYSA-N
Appearance:
Light Yellow Solid
Synonyms:
SCR7 pyrazine; SCR-7 pyrazine; SCR 7 pyrazine; 2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone; 2-mercapto-6,7-diphenylpteridin-4-ol; 6,7-diphenyl-2-sulfanylpteridin-4-ol