BGC > Product Search > Blu554 | 1707289-21-1

Molecular Formula: C24H24Cl2N4O4
Molecular Weight: 503.37776

Description:
BLU-554 is a potent and selective inhibitor of fibroblast growth factor receptor 4 (FGFR4) (IC50 = 5 nM), which is promisingly to be used for the treatment of hepatocellular carcinoma and cholangiocarcinoma.

• Molecular Weight:503.38
• Purity:99.08 %

Molecular Formula:
C24H24Cl2N4O4
Canonical SMILES:
COC1=CC(=C(C(=C1Cl)C2=CC3=CN=C(N=C3C=C2)NC4COCCC4NC(=O)C=C)Cl)OC
InChI:
InChI=1S/C24H24Cl2N4O4/c1-4-20(31)28-16-7-8-34-12-17(16)30-24-27-11-14-9-13(5-6-15(14)29-24)21-22(25)18(32-2)10-19(33-3)23(21)26/h4-6,9-11,16-17H,1,7-8,12H2,2-3H3,(H,28,31)(H,27,29,30)/t16-,17+/m0/s1
InChIKey:
MGZKYOAQVGSSGC-DLBZAZTESA-N
Solubility:
DMSO Solubility: 100 mg/mL warmed (198.65 mM)
Appearance:
Solid Powder
Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).
Synonyms:
BLU-554; BLU 554; BLU554, Fisogatinib; SCHEMBL16668287; EX-A841; MFCD30496704; N-[(3S,4S)-3-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino]oxan-4-yl]prop-2-enamide; BLU554