BGC > Product Search > Camostat mesylate | 59721-29-8

Characteristics	White to off-white crystalline powder
Solubility	Sparingly soluble in water,slightly soluble in ethanol (95%),practically insoluble in Chloroform, ether and acetone
Melting point	156-170°C
Identification	The maximum absorption at the wavelength of 265nm
Acidity	4.0-6.0
Color and clarity of solution	Conforms
Related substances(HPLC)	Total impurities NMT0.3%
Individual Impurity	NMT0.1%
Related substances(TLC )	Conforms
Water	NMT1.0%
Residue on ignition	NMT0.1%
Heavy metals	NMT0.00002%
Chloride	NMT0.02%
Assay(On dried basis)	98.0%-102.0%(C20H22N4O5.CH4O3S)

Molecular Formula: C21H26N4O8S
Molecular Weight: 494.52
Hazard Symbols: Xi,N
UN Number: UN 3077 9 / PGIII
WGKGermany: 3

Description:
Camostat (INN) or FOY-305 is a serine protease inhibitor. Serine protease enzymes have a variety of functions in the body, and so camostat has a diverse range of uses. It is used in the treatment of some forms of cancer and is also effective against some viral infections, as well as inhibiting fibrosis in liver or kidney disease orpancreatitis.

• Molecular Weight:494.52
• Boiling Point:634.6ºC at 760 mmHg
• Melting Point:162-164°C
• Purity:>98%

Molecular Formula:
C20H22N4O5.CH4O3S
Canonical SMILES:
O=C(OCC(N(C)C)=O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1.CS(=O)(O)=O
InChI:
1S/C20H22N4O5.CH4O3S/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22;1-5(2,3)4/h3-10H,11-12H2,1-2H3,(H4,21,22,23);1H3,(H,2,3,4)
InChIKey:
FSEKIHNIDBATFG-UHFFFAOYSA-N
Solubility:
In Vitro: DMSO : 125 mg/mL(252.77 mM;Need ultrasonic) H2O : ≥ 50 mg/mL(101.11 mM) In Vivo: 1.Add each solvent one by one:PBS Solubility: 12.5 mg/mL (25.28 mM); Clear solution; Need ultrasonic 2.Add each solvent one by one:10% DMSO >> 40%PEG300 >> 5%Tween-80 >> 45% saline Solubility: ≥ 2.08 mg/mL (4.21 mM); Clear solution 3.Add each solvent one by one:10% DMSO >> 90% (20%SBE-β-CDin saline) Solubility: ≥ 2.08 mg/mL (4.21 mM); Clear solution 4.Add each solvent one by one:10% DMSO >> 90%corn oil Solubility: ≥ 2.08 mg/mL (4.21 mM); Clear solution
Appearance:
Solid powder
Application:
Trypsin Inhibitors
Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months -20°C, 1 month (sealed storage, away from moisture)
Synonyms:
4-(2-(2-(dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate methanesulfonate; Camostat Mesilate; Camostat Mesylate; FOY 305; FOY-305; FOY305

Purity: 95%
Smile code: O=C(OCC(N(C)C)=O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1.CS(=O)(O)=O
MDL Number: MFCD00941410
MolFormula: C21H26N4O8S
MolWeight: 494.5181
Available in stock: 95.209

Smile code:
O=C(OCC(N(C)C)=O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1.CS(=O)(O)=O
MDL Number:
MFCD00941410
Purity :
95%
Available in stock:
69.097 g