Description:
Trandolapril is an angiotensin converting enzyme (ACE) inhibitor. It has a longer biological half-life and a high degree of lipophilicity than others. It is used to treat high blood pressure. It acts by competitive inhibition of ACE, which is a key enzyme in the renin-angiotensin system and plays an important role in regulating blood pressure. lt inhibits atherosclerosis1 and decreases the occurrence of atrial fibrillation2. It is marketed by Abbott Laboratories under the brand name Mavik. It has been listed.
- Molecular Weight:430.53
- Boiling Point:626.0±55.0°C at 760 mmHg
- Melting Point:122-123°C
- Purity:>98 %
Molecular Formula:
C24H34N2O5
Canonical SMILES:
CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCCC3CC2C(=O)O
InChI:
InChI=1S/C24H34N2O5/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29)/t16-,18+,19-,20-,21-/m0/s1
InChIKey:
VXFJYXUZANRPDJ-WTNASJBWSA-N
Solubility:
Soluble in DMSO
Appearance:
white Powder
Application:
Trandolapril is used to treat high blood pressure.
Storage: Store at RT
Synonyms:
RU 44570; (2S,3aR,7aS)-1-[(S)-N-[(S)-1-Carboxy-3-phenylpropyl] alanyl] hexahydro-2-indolinecarboxylic acid 1-ethyl ester More details are to be found
here