BGC > Product Search > 9-Nitro-20(S)-camptothecin | 91421-42-0

Molecular Formula: C20H15N3O6
Molecular Weight: 393.35
WGKGermany: 3
HS Code: 29399990

Description:
Rubitecan is a semisynthetic agent related to camptothecin with potent antitumor and antiviral properties. Rubitecan binds to and inhibits the enzyme topoisomerase I and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells. This agent also prevents repair of reversible single-strand DNA breaks.

• Molecular Weight:393.35
• Boiling Point:816.3±65.0°C (Predicted)
• Melting Point:>255°C (dec.)
• Purity:≥98%

Molecular Formula:
C20H15N3O6
Canonical SMILES:
CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC=C(C5=C4)[N+](=O)[O-])O
InChI:
InChI=1S/C20H15N3O6/c1-2-20(26)13-7-16-17-10(8-22(16)18(24)12(13)9-29-19(20)25)6-11-14(21-17)4-3-5-15(11)23(27)28/h3-7,26H,2,8-9H2,1H3/t20-/m0/s1
InChIKey:
VHXNKPBCCMUMSW-FQEVSTJZSA-N
Solubility:
Soluble in Chloroform, DMSO, Methanol
Appearance:
Yellow Solid
Storage: Store at -20°C
Synonyms:
RFS 2000; 9-Nitrocamptothecin; (4S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizinol[1,2-b]quinoline-3,14(4H,12H)-dione; 9-NC; Orathecin; 9-nitro-20(S)-camptothecin; Camptogen; (S)-4-Ethyl-4-hydroxy-10-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 9-nitro-CPT; Nitrocamptothecin

Assay: 98%min
Specification: Pharmacopeia Standard or Enterprise Standard
Alternative repackage service: 1G, 5G, 10G, 20G etc
We are supplying customers with good quality and competitive price
Please contact us for business