Description:
Amlodipine EP Impurity E is an impurity of Amlodipine. Amlodipine is a long-acting dihydropyridine L-type calcium channel blocker. Amlodipine is used to lower blood pressure and prevent chest pain.
- Molecular Weight:422.90
- Melting Point:106-108°C
- Purity:>95%
Molecular Formula:
C21H27ClN2O5
Canonical SMILES:
CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OCC)COCCN)C
InChI:
InChI=1S/C21H27ClN2O5/c1-4-28-20(25)17-13(3)24-16(12-27-11-10-23)19(21(26)29-5-2)18(17)14-8-6-7-9-15(14)22/h6-9,18,24H,4-5,10-12,23H2,1-3H3
InChIKey:
BGGLOZPVAWMSEB-UHFFFAOYSA-N
Solubility:
Soluble in DMSO, Methanol
Appearance:
White to Off-white Solid
Application:
Amlodipine Besilate (A633500) impurity.
Storage: Store at 2-8°C
Synonyms:
Amlodipine USP Related Compound E; Amlodipine Diethyl Ester; 2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylic acid diethyl ester; 3-Ethyl 5-Ethyl 4-(2-Chlorophenyl)-6-methyl-2-[[2-[(2-aminoethoxy)methyl]-1,4-dihydropyridine-3,5-dicarboxylate More details are to be found
here