BGC > Product Search > Pazopanib | 444731-52-6

Molecular Formula: C21H23N7O2S
Molecular Weight: 437.52
HS Code: 29350090

Description:
Pazopanib is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively.

• Molecular Weight:437.52
• Purity:>98%

Molecular Formula:
C21H23N7O2S
Canonical SMILES:
CC1=C(C=C(C=C1)NC2=NC=CC(=N2)N(C)C3=CC4=NN(C(=C4C=C3)C)C)S(=O)(=O)N
InChI:
InChI=1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25)
InChIKey:
CUIHSIWYWATEQL-UHFFFAOYSA-N
Application:
Anticancer reagents
Synonyms:
GW786034; GW786034; GW 786034; Pazopanib; US brand name: Votrient.