BGC > Product Search > Ertapenem sodium | 153773-82-1

Molecular Formula: C22H24N3O7S.Na
Molecular Weight: 497.502

Molecular Formula: C22H25N3O7S.Na
Molecular Weight: 498.51

Description:
Ertapenem Sodium is the sodium salt of ertapenem. Ertapenem has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of ertapenem results from the inhibition of cell wall synthesis and is mediated through ertapenem binding to penicillin binding proteins (PBPs). In Escherichia coli, it has strong affinity toward PBPs 1a, 1b, 2, 3, 4 and 5 with preference for PBPs 2 and 3. Ertapenem is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases. Ertapenem is hydrolyzed by metallo-beta-lactamases. Ertapenem has been shown to be active against most isolates of the following microorganisms in vitro and in clinical infections.

• Molecular Weight:497.50
• Boiling Point:813.9°C at 760 mmHg
• Purity:98%

Molecular Formula:
C22H24N3NaO7S
Canonical SMILES:
CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)NC4=CC=CC(=C4)C(=O)[O-])C(=O)O)C(C)O.[Na+]
InChI:
InChI=1S/C22H25N3O7S.Na/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30;/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32);/q;+1/p-1/t9-,10-,13+,14+,15-,16-;/m1./s1
InChIKey:
ZXNAQFZBWUNWJM-HRXMHBOMSA-M
Solubility:
Soluble in DMSO
Appearance:
White to Light Yellow Solid
Storage: Store at -20°C
Synonyms:
Invanz; Ertapenem sodium salt; MK-0826