Suppliers for CAS
143664-11-3
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Properties | CAS |
143664-11-3 | Formula |
C34H33N3O5 |
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13 Registered suppliers
H&Z Industry Co.,Ltd
P.R.China
Xingrui Industry Co., Limited
P.R.China
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C34H33N3O5 Molecular Weight: 563.64292 WGKGermany: 3 HS Code: 29334900
More details are to be found here
Create Chemical Co., Ltd.
P.R.China
Shandong Lanhai Industry Co.,Ltd.
P.R.China
Aea.ltd
P.R.China
Lori Industry Co., Ltd
P.R.China
BOC Sciences
USA
Description: Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects. Molecular Formula: C34H33N3O5 Canonical SMILES: COC1=CC=CC2=C1NC3=C(C2=O)C=CC=C3C(=O)NC4=CC=C(C=C4)CCN5CCC6=CC(=C(C=C6C5)OC)OC InChI: InChI=1S/C34H33N3O5/c1-40-28-9-5-7-26-32(28)36-31-25(33(26)38)6-4-8-27(31)34(39)35-24-12-10-21(11-13-24)14-16-37-17-15-22-18-29(41-2)30(42-3)19-23(22)20-37/h4-13,18-19H,14-17,20H2,1-3H3,(H,35,39)(H,36,38) InChIKey: OSFCMRGOZNQUSW-UHFFFAOYSA-N Appearance: Yellow solid powder Synonyms: GF120918; GF-120918; GF 120918; GF-120918A; GF120918A; GF 120918A; GG 918; D03968. Elacridar hydrochloride. More details are to be found here
Ambeed, Inc.
USA
Purity: 98% Smile code: O=C(C(C=CC=C1C2=O)=C1NC3=C2C=CC=C3OC)NC4=CC=C(CCN5CC6=C(C=C(OC)C(OC)=C6)CC5)C=C4 MDL Number: MFCD00912604 MolFormula: C34H33N3O5 MolWeight: 563.6429 Available in stock: 18.75 More details are to be found here
BLD Pharmatech Ltd
P.R.China
Smile code:O=C(C(C=CC=C1C2=O)=C1NC3=C2C=CC=C3OC)NC4=CC=C(CCN5CC6=C(C=C(OC)C(OC)=C6)CC5)C=C4 MDL Number:MFCD00912604 Purity :98% Available in stock: 25.438 g More details are to be found here
Chemos GmbH & Co. KG
Germany
BuGuCh & Partners
Germany
Santa Cruz Biotechnology, Inc.
USA
Detailed information on the suppliers of
Elacridar
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