BGC > CAS Search > 67915-31-5

Molecular Formula: C26H31Cl2N5O3
Molecular Weight: 532.46
Hazard Symbols: Xi
WGKGermany: 3
HS Code: 2934990002

Description:
Terconazole is an antifungal drug used to treat vaginal yeast infection. It has a relatively broad spectrum compared to azole compounds. It may exert its antifungal activity by disrupting normal fungal cell membrane permeability. It comes as a lotion or a suppository and disrupts the biosynthesis of fats in a yeast cell. It is a suitable compound for prophylaxis for those that suffer from chronic vulvovaginal candidiasis. It has a far greater selectively for yeast cytochrome P-450 than for mammalian microsomal cytochrome P-450. It may also be used in vitro to prevent the morphogenetic transformation of yeast into (pseudo-)mycelium form of Candida albicans. It was developed by Johnson & Johnson and has been listed.

• Molecular Weight:532.46
• Boiling Point:681.8±65.0 °C | Condition: Press: 760 Torr
• Melting Point:125-127°C
• Purity:98%

Molecular Formula:
C26H31Cl2N5O3
Canonical SMILES:
ClC1=CC=C(C(Cl)=C1)C2(OCC(O2)COC3=CC=C(C=C3)N4CCN(CC4)C(C)C)CN5N=CN=C5
InChI:
InChI=1S/C26H31Cl2N5O3/c1-19(2)31-9-11-32(12-10-31)21-4-6-22(7-5-21)34-14-23-15-35-26(36-23,16-33-18-29-17-30-33)24-8-3-20(27)13-25(24)28/h3-8,13,17-19,23H,9-12,14-16H2,1-2H3/t23-,26-/s2
InChIKey:
BLSQLHNBWJLIBQ-MKNUCDGGNA-N
Solubility:
Soluble in Chloroform (Slightly), Methanol (Slightly)
Appearance:
White Solid
Application:
Terconazole is an antifungal drug used to treat vaginal yeast infection. It may also be used in vitro to prevent the morphogenetic transformation of yeast into (pseudo-)mycelium form of Candida albicans.
Storage: Store at 2-8°C
Synonyms:
Piperazine, 1-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)-, cis-; cis-1-(p-{[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine; Piperazine, 1-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)-, rel-; rel-1-[4-[[(2R,4S)-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-4-(1-methylethyl)piperazine; (±)-Terconazole; Fungistat; Gyno-Terazol; NSC 331942; R 42470; Terazol; Tercospor; Termayazole; Triaconazole

Purity: 97%
Smile code: CC(N1CCN(C2=CC=C(OC[C@@H]3O[C@](C4=CC=C(Cl)C=C4Cl)(CN5N=CN=C5)OC3)C=C2)CC1)C
MDL Number: MFCD05662369
MolFormula: C26H31Cl2N5O3
MolWeight: 532.4620
Available in stock: 19.102

Smile code:
CC(N1CCN(C2=CC=C(OC[C@@H]3O[C@](C4=CC=C(Cl)C=C4Cl)(CN5N=CN=C5)OC3)C=C2)CC1)C
MDL Number:
MFCD05662369
Purity :
97%
Available in stock:
16.47 g