BGC > CAS Search > 6877-32-3

Molecular Formula: C22H28N2O4
Molecular Weight: 384.473

Molecular Formula: C22H28N2O4
Molecular Weight: 384.473

Molecular Formula: C22H28N2O4
Molecular Weight: 384.473

Description :
Corynoxine is an enantiomer of Corynoxine B. It induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells. By inducing autophagy, it promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. It also significantly decreased locomotor activity after oral administration to mice.

• Molecular Weight :384.47
• Boiling Point :560.8±50.0°C (Predicted)
• Melting Point :166-168℃
• Purity :> 98%

Molecular Formula :
C22H28N2O4
Canonical SMILES :
CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O
InChI :
InChI=1S/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)/b16-13+/t14-,15+,19+,22+/m1/s1
InChIKey :
DAXYUDFNWXHGBE-NRAMRBJXSA-N
Appearance :
Cryst.
Synonyms :
(16E)-16,17-Didehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester

More details are to be found here

Description :
Corynoxine is an enantiomer of Corynoxine B. It induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells. By inducing autophagy, it promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. It also significantly decreased locomotor activity after oral administration to mice.

• Molecular Weight :384.47
• Boiling Point :560.8±50.0°C (Predicted)
• Melting Point :166-168℃
• Purity :> 98%

Molecular Formula :
C22H28N2O4
Canonical SMILES :
CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C4=CC=CC=C4NC3=O
InChI :
InChI=1S/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)/b16-13+/t14-,15+,19+,22+/m1/s1
InChIKey :
DAXYUDFNWXHGBE-NRAMRBJXSA-N
Appearance :
Cryst.
Synonyms :
(16E)-16,17-Didehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester

More details are to be found here