BGC > CAS Search > 58694-52-3

Molecular Formula: C106H180N34O23S5
Molecular Weight: 2459.13

Description :
Tertiapin is a 21-amino acid peptide isolated from the venom of the honey bee (Apis mellifera). It was shown to block inward rectifier potassium channels (Kir) and calcium activated large conductance potassium channels (BK).

• Molecular Weight :2459.14
• Purity :≥95% by HPLC

Molecular Formula :
C106H180N34O23S5
Canonical SMILES :
O=C(N)CC(NC(=O)C(NC(=O)C(NC(=O)C(N)C)CC(C)C)CS)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N)CCCCN)CCCCN)CS)CCCCN)CCCCN)CC2=CNC=3C=CC=CC32)CS)CCSC)CC4=CN=CN4)C(C)CC)C(C)CC)C(C)CC)CCCNC(=N)N)CC(=O)N)CS
InChI :
InChI=1S/C106H180N34O23S5/c1-11-56(6)83(137-93(151)68(32-24-39-118-106(115)116)126-97(155)73(45-80(112)141)130-101(159)78(53-167)136-98(156)74(46-81(113)142)131-100(158)77(52-166)135-94(152)70(42-55(4)5)128-87(145)59(9)111)103(161)138-84(57(7)12-2)104(162)139-85(58(8)13-3)105(163)140-40-25-33-79(140)102(160)132-72(44-61-48-117-54-121-61)96(154)127-69(34-41-168-10)92(150)134-76(51-165)99(157)129-71(43-60-47-119-63-27-15-14-26-62(60)63)95(153)125-66(30-18-22-37-109)90(148)124-67(31-19-23-38-110)91(149)133-75(50-164)88(146)120-49-82(143)122-65(29-17-21-36-108)89(147)123-64(86(114)144)28-16-20-35-107/h14-15,26-27,47-48,54-59,64-79,83-85,119,164-167H,11-13,16-25,28-46,49-53,107-111H2,1-10H3,(H2,112,141)(H2,113,142)(H2,114,144)(H,117,121)(H,120,146)(H,122,143)(H,123,147)(H,124,148)(H,125,153)(H,126,155)(H,127,154)(H,128,145)(H,129,157)(H,130,159)(H,131,158)(H,132,160)(H,133,149)(H,134,150)(H,135,152)(H,136,156)(H,137,151)(H,138,161)(H,139,162)(H4,115,116,118)/t56-,57-,58-,59-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,83-,84-,85-/m0/s1
InChIKey :
YUJSAJLRLLRZPV-YJOCJKAQSA-N
Solubility :
Soluble in Water
Appearance :
White Lyophilized Powder
Storage : Store at -20°C
Synonyms :
H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Met-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2; L-Alanyl-L-leucyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-asparaginyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-isoleucyl-L-prolyl-L-histidyl-L-methionyl-L-cysteinyl-L-tryptophyl-L-lysyl-L-lysyl-L-cysteinylglycyl-L-lysyl-L-lysinamide; Tertiapin (reduced)

More details are to be found here

Description :
Tertiapin is a 21-amino acid peptide isolated from the venom of the honey bee (Apis mellifera). It was shown to block inward rectifier potassium channels (Kir) and calcium activated large conductance potassium channels (BK).

• Molecular Weight :2459.14
• Purity :≥95% by HPLC

Molecular Formula :
C106H180N34O23S5
Canonical SMILES :
O=C(N)CC(NC(=O)C(NC(=O)C(NC(=O)C(N)C)CC(C)C)CS)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N)CCCCN)CCCCN)CS)CCCCN)CCCCN)CC2=CNC=3C=CC=CC32)CS)CCSC)CC4=CN=CN4)C(C)CC)C(C)CC)C(C)CC)CCCNC(=N)N)CC(=O)N)CS
InChI :
InChI=1S/C106H180N34O23S5/c1-11-56(6)83(137-93(151)68(32-24-39-118-106(115)116)126-97(155)73(45-80(112)141)130-101(159)78(53-167)136-98(156)74(46-81(113)142)131-100(158)77(52-166)135-94(152)70(42-55(4)5)128-87(145)59(9)111)103(161)138-84(57(7)12-2)104(162)139-85(58(8)13-3)105(163)140-40-25-33-79(140)102(160)132-72(44-61-48-117-54-121-61)96(154)127-69(34-41-168-10)92(150)134-76(51-165)99(157)129-71(43-60-47-119-63-27-15-14-26-62(60)63)95(153)125-66(30-18-22-37-109)90(148)124-67(31-19-23-38-110)91(149)133-75(50-164)88(146)120-49-82(143)122-65(29-17-21-36-108)89(147)123-64(86(114)144)28-16-20-35-107/h14-15,26-27,47-48,54-59,64-79,83-85,119,164-167H,11-13,16-25,28-46,49-53,107-111H2,1-10H3,(H2,112,141)(H2,113,142)(H2,114,144)(H,117,121)(H,120,146)(H,122,143)(H,123,147)(H,124,148)(H,125,153)(H,126,155)(H,127,154)(H,128,145)(H,129,157)(H,130,159)(H,131,158)(H,132,160)(H,133,149)(H,134,150)(H,135,152)(H,136,156)(H,137,151)(H,138,161)(H,139,162)(H4,115,116,118)/t56-,57-,58-,59-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,83-,84-,85-/m0/s1
InChIKey :
YUJSAJLRLLRZPV-YJOCJKAQSA-N
Solubility :
Soluble in Water
Appearance :
White Lyophilized Powder
Storage : Store at -20°C
Synonyms :
H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Met-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2; L-Alanyl-L-leucyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-asparaginyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-isoleucyl-L-prolyl-L-histidyl-L-methionyl-L-cysteinyl-L-tryptophyl-L-lysyl-L-lysyl-L-cysteinylglycyl-L-lysyl-L-lysinamide; Tertiapin (reduced)

More details are to be found here

Description :
Tertiapin is a 21-amino acid peptide isolated from the venom of the honey bee (Apis mellifera). It was shown to block inward rectifier potassium channels (Kir) and calcium activated large conductance potassium channels (BK).

• Molecular Weight :2459.14
• Purity :≥95% by HPLC

Molecular Formula :
C106H180N34O23S5
Canonical SMILES :
O=C(N)CC(NC(=O)C(NC(=O)C(NC(=O)C(N)C)CC(C)C)CS)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N)CCCCN)CCCCN)CS)CCCCN)CCCCN)CC2=CNC=3C=CC=CC32)CS)CCSC)CC4=CN=CN4)C(C)CC)C(C)CC)C(C)CC)CCCNC(=N)N)CC(=O)N)CS
InChI :
InChI=1S/C106H180N34O23S5/c1-11-56(6)83(137-93(151)68(32-24-39-118-106(115)116)126-97(155)73(45-80(112)141)130-101(159)78(53-167)136-98(156)74(46-81(113)142)131-100(158)77(52-166)135-94(152)70(42-55(4)5)128-87(145)59(9)111)103(161)138-84(57(7)12-2)104(162)139-85(58(8)13-3)105(163)140-40-25-33-79(140)102(160)132-72(44-61-48-117-54-121-61)96(154)127-69(34-41-168-10)92(150)134-76(51-165)99(157)129-71(43-60-47-119-63-27-15-14-26-62(60)63)95(153)125-66(30-18-22-37-109)90(148)124-67(31-19-23-38-110)91(149)133-75(50-164)88(146)120-49-82(143)122-65(29-17-21-36-108)89(147)123-64(86(114)144)28-16-20-35-107/h14-15,26-27,47-48,54-59,64-79,83-85,119,164-167H,11-13,16-25,28-46,49-53,107-111H2,1-10H3,(H2,112,141)(H2,113,142)(H2,114,144)(H,117,121)(H,120,146)(H,122,143)(H,123,147)(H,124,148)(H,125,153)(H,126,155)(H,127,154)(H,128,145)(H,129,157)(H,130,159)(H,131,158)(H,132,160)(H,133,149)(H,134,150)(H,135,152)(H,136,156)(H,137,151)(H,138,161)(H,139,162)(H4,115,116,118)/t56-,57-,58-,59-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,83-,84-,85-/m0/s1
InChIKey :
YUJSAJLRLLRZPV-YJOCJKAQSA-N
Solubility :
Soluble in Water
Appearance :
White Lyophilized Powder
Storage : Store at -20°C
Synonyms :
H-Ala-Leu-Cys-Asn-Cys-Asn-Arg-Ile-Ile-Ile-Pro-His-Met-Cys-Trp-Lys-Lys-Cys-Gly-Lys-Lys-NH2; L-Alanyl-L-leucyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-asparaginyl-L-arginyl-L-isoleucyl-L-isoleucyl-L-isoleucyl-L-prolyl-L-histidyl-L-methionyl-L-cysteinyl-L-tryptophyl-L-lysyl-L-lysyl-L-cysteinylglycyl-L-lysyl-L-lysinamide; Tertiapin (reduced)

More details are to be found here