BGC > CAS Search > 47491-38-3

Molecular Formula: C21H22ClN3O

Description :
N-Desmethyl Azelastine is the main metabolite of Azelastine. Azelastine is a potent, selective and second-generation histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor.

• Molecular Weight :367.88
• Melting Point :90-95°C
• Purity :> 95%

Molecular Formula :
C21H22ClN3O
Canonical SMILES :
C1CC(CCNC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl
InChI :
InChI=1S/C21H22ClN3O/c22-16-9-7-15(8-10-16)14-20-18-5-1-2-6-19(18)21(26)25(24-20)17-4-3-12-23-13-11-17/h1-2,5-10,17,23H,3-4,11-14H2
InChIKey :
WRYCMIFVXDQIKN-UHFFFAOYSA-N
Appearance :
Pale Yellow Solid
Synonyms :
Desmethylazelastine; 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1H-azepin-4-yl)-1(2H)-phthalazinone; Azelastine Hydrochloride Impurity

More details are to be found here

Description :
N-Desmethyl Azelastine is the main metabolite of Azelastine. Azelastine is a potent, selective and second-generation histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor.

• Molecular Weight :367.88
• Melting Point :90-95°C
• Purity :> 95%

Molecular Formula :
C21H22ClN3O
Canonical SMILES :
C1CC(CCNC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl
InChI :
InChI=1S/C21H22ClN3O/c22-16-9-7-15(8-10-16)14-20-18-5-1-2-6-19(18)21(26)25(24-20)17-4-3-12-23-13-11-17/h1-2,5-10,17,23H,3-4,11-14H2
InChIKey :
WRYCMIFVXDQIKN-UHFFFAOYSA-N
Appearance :
Pale Yellow Solid
Synonyms :
Desmethylazelastine; 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1H-azepin-4-yl)-1(2H)-phthalazinone; Azelastine Hydrochloride Impurity

More details are to be found here

Description :
N-Desmethyl Azelastine is the main metabolite of Azelastine. Azelastine is a potent, selective and second-generation histamine antagonist. It inhibits histamine via competing with histamine for the H1 receptor.

• Molecular Weight :367.88
• Melting Point :90-95°C
• Purity :> 95%

Molecular Formula :
C21H22ClN3O
Canonical SMILES :
C1CC(CCNC1)N2C(=O)C3=CC=CC=C3C(=N2)CC4=CC=C(C=C4)Cl
InChI :
InChI=1S/C21H22ClN3O/c22-16-9-7-15(8-10-16)14-20-18-5-1-2-6-19(18)21(26)25(24-20)17-4-3-12-23-13-11-17/h1-2,5-10,17,23H,3-4,11-14H2
InChIKey :
WRYCMIFVXDQIKN-UHFFFAOYSA-N
Appearance :
Pale Yellow Solid
Synonyms :
Desmethylazelastine; 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1H-azepin-4-yl)-1(2H)-phthalazinone; Azelastine Hydrochloride Impurity

More details are to be found here