BGC > CAS Search > 197855-65-5

Molecular Formula: C21H23FN2O4
Molecular Weight: 386.42
HS Code: 29145090

Molecular Formula: C21H23FN2O4
Molecular Weight: 386.42
WGKGermany: 3

Description :
Z-FA-FMK is an irreversible cysteine protease inhibitor, and it also inhibits caspases-2, -3, -6, and -7. Z-FA-FMK suppresses the degradation of fibrillar collagen by fibroblasts and osteoclasts, and reduces LPS-induced cytokine production via inhibition of NF-kappaB-dependent gene expression in macrophages.

• Molecular Weight :386.42
• Boiling Point :630.5±55.0°C (Predicted)
• Purity :≥95%

Molecular Formula :
C21H23FN2O4
Canonical SMILES :
CC(C(=O)CF)NC(=O)C(CC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2
InChI :
InChI=1S/C21H23FN2O4/c1-15(19(25)13-22)23-20(26)18(12-16-8-4-2-5-9-16)24-21(27)28-14-17-10-6-3-7-11-17/h2-11,15,18H,12-14H2,1H3,(H,23,26)(H,24,27)/t15?,18-/m0/s1
InChIKey :
ASXVEBPEZMSPHB-PKHIMPSTSA-N
Solubility :
Soluble in DMSO
Appearance :
White solid
Application :
Cysteine Proteinase Inhibitors
Storage : Store at -20°C
Synonyms :
Z-Phe-DL-Ala-fluoromethylketone; Zfa-fmk; benzyloxycarbonyl-Phe-Ala-fluormethylketone; benzyloxycarbonylphenylalanyl-alanine fluoromethyl ketone; Carbamic acid, N-((1S)-2-((3-fluoro-1-methyl-2-oxopropyl)amino)-2-oxo-1-(phenylmethyl)ethyl)-, phenylmethyl ester

More details are to be found here

Description :
Z-FA-FMK is an irreversible cysteine protease inhibitor, and it also inhibits caspases-2, -3, -6, and -7. Z-FA-FMK suppresses the degradation of fibrillar collagen by fibroblasts and osteoclasts, and reduces LPS-induced cytokine production via inhibition of NF-kappaB-dependent gene expression in macrophages.

• Molecular Weight :386.42
• Boiling Point :630.5±55.0°C (Predicted)
• Purity :≥95%

Molecular Formula :
C21H23FN2O4
Canonical SMILES :
CC(C(=O)CF)NC(=O)C(CC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2
InChI :
InChI=1S/C21H23FN2O4/c1-15(19(25)13-22)23-20(26)18(12-16-8-4-2-5-9-16)24-21(27)28-14-17-10-6-3-7-11-17/h2-11,15,18H,12-14H2,1H3,(H,23,26)(H,24,27)/t15?,18-/m0/s1
InChIKey :
ASXVEBPEZMSPHB-PKHIMPSTSA-N
Solubility :
Soluble in DMSO
Appearance :
White solid
Application :
Cysteine Proteinase Inhibitors
Storage : Store at -20°C
Synonyms :
Z-Phe-DL-Ala-fluoromethylketone; Zfa-fmk; benzyloxycarbonyl-Phe-Ala-fluormethylketone; benzyloxycarbonylphenylalanyl-alanine fluoromethyl ketone; Carbamic acid, N-((1S)-2-((3-fluoro-1-methyl-2-oxopropyl)amino)-2-oxo-1-(phenylmethyl)ethyl)-, phenylmethyl ester

More details are to be found here

Description :
Z-FA-FMK is an irreversible cysteine protease inhibitor, and it also inhibits caspases-2, -3, -6, and -7. Z-FA-FMK suppresses the degradation of fibrillar collagen by fibroblasts and osteoclasts, and reduces LPS-induced cytokine production via inhibition of NF-kappaB-dependent gene expression in macrophages.

• Molecular Weight :386.42
• Boiling Point :630.5±55.0°C (Predicted)
• Purity :≥95%

Molecular Formula :
C21H23FN2O4
Canonical SMILES :
CC(C(=O)CF)NC(=O)C(CC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2
InChI :
InChI=1S/C21H23FN2O4/c1-15(19(25)13-22)23-20(26)18(12-16-8-4-2-5-9-16)24-21(27)28-14-17-10-6-3-7-11-17/h2-11,15,18H,12-14H2,1H3,(H,23,26)(H,24,27)/t15?,18-/m0/s1
InChIKey :
ASXVEBPEZMSPHB-PKHIMPSTSA-N
Solubility :
Soluble in DMSO
Appearance :
White solid
Application :
Cysteine Proteinase Inhibitors
Storage : Store at -20°C
Synonyms :
Z-Phe-DL-Ala-fluoromethylketone; Zfa-fmk; benzyloxycarbonyl-Phe-Ala-fluormethylketone; benzyloxycarbonylphenylalanyl-alanine fluoromethyl ketone; Carbamic acid, N-((1S)-2-((3-fluoro-1-methyl-2-oxopropyl)amino)-2-oxo-1-(phenylmethyl)ethyl)-, phenylmethyl ester

More details are to be found here