BGC > CAS Search > 1405-20-5

Description	White to light yellow powder
Identification	Passes tests
PH(0.5% Solution)	5.0-7.5
Loss on drying(60℃ ,3hours)	≤ 7.0%
Content of phenylalanine(Calculated on the dried basis)	9%-12%
Microbial limit
Number of bacteria colonies	Not more than 10/G
Number of fungiand yeasts colonies	Not more than 10/G
Number of ecoli colonies	Should not be found
Assay(Calculated on the dried basis)	Not less than 6000 polymyxin B unites per mg.

Molecular Formula: C56H98N16O13.H2SO4
Molecular Weight: 1301.56

EINECS: 215-774-7
Molecular formula: C56H98N16O13.H2SO4

Alternative name	Polymyxin B sulfat, API (mikrobielle Herkunft)
Further description	Polymyxini B sulfas
Monograph	Ph.Eur.9.7
Pharmaceutical status	prescription only
UEXDES	Chemicals solid

Description:
Polymyxin B is an antibiotic produced by Bacillus polymyxia strains. It is effective against gram-negative infections.

• Molecular Weight:1301.56
• Boiling Point:1651°C at 760 mmHg
• Melting Point:18°C

Molecular Formula:
C56H100N16O17S
Canonical SMILES:
CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)C(C)O.OS(=O)(=O)O
InChI:
InChI=1S/C56H98N16O13.H2O4S/c1-7-32(4)13-11-12-16-44(75)63-36(17-23-57)51(80)72-46(34(6)74)56(85)68-39(20-26-60)48(77)67-41-22-28-62-55(84)45(33(5)73)71-52(81)40(21-27-61)65-47(76)37(18-24-58)66-53(82)42(29-31(2)3)69-54(83)43(30-35-14-9-8-10-15-35)70-49(78)38(19-25-59)64-50(41)79;1-5(2,3)4/h8-10,14-15,31-34,36-43,45-46,73-74H,7,11-13,16-30,57-61H2,1-6H3,(H,62,84)(H,63,75)(H,64,79)(H,65,76)(H,66,82)(H,67,77)(H,68,85)(H,69,83)(H,70,78)(H,71,81)(H,72,80);(H2,1,2,3,4)
InChIKey:
HFMDLUQUEXNBOP-UHFFFAOYSA-N
Solubility:
Soluble in DMSO
Appearance:
powder
Storage: RT
Synonyms:
Aerosporin; PMB; Poly-RX