BGC > CAS Search > 1197996-80-7

Molecular Formula: C21H24N2O2
Molecular Weight: 336.42746

Molecular Formula: C21H24N2O2
Molecular Weight: 336.42746

Description :
CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-κB with an EC50 of 0.47 µM. It also inhibits histone chaperone FACT (facilitates chromatin transcription) and MYC signal.

• Molecular Weight :336.435

Molecular Formula :
C21H24N2O2
Canonical SMILES :
CC(C)NCCN1C2=C(C=C(C=C2)C(=O)C)C3=C1C=CC(=C3)C(=O)C
InChI :
InChI=1S/C21H24N2O2/c1-13(2)22-9-10-23-20-7-5-16(14(3)24)11-18(20)19-12-17(15(4)25)6-8-21(19)23/h5-8,11-13,22H,9-10H2,1-4H3
InChIKey :
JKCSODVERGVDLT-UHFFFAOYSA-N
Synonyms :
CBL0137; CBL-0137; CBL 0137; CBLC137; CBLC-137; CBLC 137; Curaxin 137; 1,1'-(9-(2-(Isopropylamino)ethyl)-9H-carbazole-3,6-diyl)diethanone; 1-[6-acetyl-9-[2-(propan-2-ylamino)ethyl]carbazol-3-yl]ethanone

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