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Suppliers for CAS
755037-03-7
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Properties | | CAS |
755037-03-7 | | Formula |
C21H15ClF4N4O3 |
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13 Registered suppliers
Amadis Chemical Company Limited
P.R.China
Dayang Chem (Hangzhou) Co.,Ltd.
P.R.China
Hangzhou Keying Chem Co., Ltd.
P.R.China
H&Z Industry Co.,Ltd
P.R.China
Hangzhou Meite Industry Co., Ltd (Hangzhou Meite Chemical Co., Ltd)
P.R.China
Capot Chemical Co., Ltd.
P.R.China
More details are to be found here
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C21H15ClF4N4O3
Molecular Weight: 482.8154128
HS Code: 29242990
Aea.ltd
P.R.China
Molecular Formula: C21H15ClF4N4O3
Molecular Weight: 482.8154128
HS Code: 29242990
Molecular Formula: C21H15ClF4N4O3
Molecular Weight: 482.8154128
HS Code: 29242990
Hangzhou Zhongqi Chem Co., Ltd
P.R.China
Molecular Formula: C21H15ClF4N4O3
Molecular Weight: 482.8154128
HS Code: 29242990
Skyrun Industrial Co., Ltd.
P.R.China
Molecular Formula: C21H15ClF4N4O3
Molecular Weight: 482.8154128
HS Code: 29242990
BOC Sciences
USA
Description : Regorafenib, also known as BAY 73-4506, is an orally bioavailable small molecule with potential antiangiogenic and antineoplastic activities. Regorafenib binds to and inhibits vascular endothelial growth factor receptors (VEGFRs) 2 and 3, and Ret, Kit, PDGFR and Raf kinases, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation. VEGFRs are receptor tyrosine kinases that play important roles in tumor angiogenesis; the receptor tyrosine kinases RET, KIT, and PDGFR, and the serine/threonine-specific Raf kinase are involved in tumor cell signaling. Regorafenib is demonstrated to increase the overall survival of patients with metastatic colorectal cancer and has been approved by the US FDA on September 27, 2012. - Molecular Weight :482.83
- Boiling Point :513.4±50.0°C (Predicted)
- Melting Point :203-205°C
- Purity :> 98%
Molecular Formula : C21H15ClF4N4O3 Canonical SMILES : CNC(=O)C1=NC=CC(=C1)OC2=CC(=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)F
InChI :
InChI=1S/C21H15ClF4N4O3/c1-27-19(31)18-10-13(6-7-28-18)33-12-3-5-17(16(23)9-12)30-20(32)29-11-2-4-15(22)14(8-11)21(24,25)26/h2-10H,1H3,(H,27,31)(H2,29,30,32)
InChIKey :
FNHKPVJBJVTLMP-UHFFFAOYSA-N
Solubility :
Soluble in DMSO (Slightly), Methanol (Slightly)
Appearance :
Pale Pink to Light Pink Solid
Application :
antineoplastic agent
Storage : Store at 2-8°C
Synonyms :
4-[4-[[[[4-Chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide; 4-[4-[N'-(4-Chloro-3-trifluoromethylphenyl)ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; Regorafenibum; Stivarga; 4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide; BAY 73-4506; BAY 734506; BAY734506; BAY-734506
More details are to be found here
Allfluoro Pharmaceutical Co. Ltd.
P.R.China
MDL: MFCD16038047
MF: C21H15CLF4N4O3
MW: 482,82
Chemos GmbH & Co. KG
Germany
MDL: MFCD16038047
MF: C21H15CLF4N4O3
MW: 482,82
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